Research advancement on mechanism of dorsal root ganglia neurons apoptosis induced by platinum-based drug / 国外医学(肿瘤学分册)

ABSTRACT

Cisplatin,carpolatin and oxaliplatin are platinum-based drugs that are widely used in cancer chemotherapy. Peripheral neuropathy is major dose-limiting side effect of platinum-based drug. Accordingly, this side effect restrict its clinic application. This review will focus on the research advancement on the mechanism of dorsal root ganglia neurons apoptosis in cellular and molecular biology.