Progress in the development of antineoplastic activity substance from marine sponge / 国外医学(肿瘤学分册)

ABSTRACT

Marine organism is important source of antineoplastic active substance,sponge is the secondly larger amount of organism source besides coral in the ocean. In recent decade, several high antineoplastic active substances with novel structure are abstracted and identified from different kinds of sponges. These discovers reveal bright prospect of research and development. This article summarized antineoplastic active sponge abstracts and their synthesis derivative which still in the clinical trials,their origins and the research development of their chemical composition and pharmacological action.