Preparation of arsenic trioxide albumin microspheres and its release characteristics in vitro / 华中科技大学学报(医学)(英德文版)
Journal of Huazhong University of Science and Technology (Medical Sciences)
;
(6): 310-2, 319, 2005.
Artículo
en Inglés
| WPRIM
| ID: wpr-641010
ABSTRACT
Arsenic trioxide albumin microspheres (As2O3-BSA-NS) were prepared by using methods of chemical cross-linking. The desirability function (DF), calculated according to the size (0.05). The release experiment in vitro showed that As2O3 in As2O3-BSA-NS was released more slower than pure As2O3. It was concluded that regular As2O3-BSA-NS may be prepared by the methods of chemical cross-linking, which was optimized by orthogonal experimental analysis of different factors, and the microspheres can release As2O3 slowly.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Óxidos
/
Arsenicales
/
Albúmina Sérica Bovina
/
Portadores de Fármacos
/
Tecnología Farmacéutica
/
Sistemas de Liberación de Medicamentos
/
Reactivos de Enlaces Cruzados
/
Preparaciones de Acción Retardada
/
Microesferas
Idioma:
Inglés
Revista:
Journal of Huazhong University of Science and Technology (Medical Sciences)
Año:
2005
Tipo del documento:
Artículo
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