The Rosai-Dorfman Disease of the Nasal Cavity and Salivary Gland: A Case Report / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
;
: 1001-1004, 2000.
Artículo
en Coreano
| WPRIM
| ID: wpr-645143
ABSTRACT
Rosai-Dorfman disease (RDD), or sinus histiocytosis with massive lymphadenopathy, is a rare idiopathic histiocytosis that most commonly involves the cervical lymph nodes, Extranodal involvement occurs in 30- 40% of cases, most often in the head and neck. Characteristic histological findings include emperiopolesis (intracellular engulfment) of lymphocytes and S-100 protein positivity. Treatment of Rosai-Dorfman disease is unnecessary unless the disorder becomes life-threatening, since the disease will resolve spontaneously in most patients. We experienced a case of extranodal RDD at the nasal cavity as the initial lesion prior its nodal involvement. The patient was a 18-year-old woman who complained of nasal obstruction for 4 years and had a submandibular mass that persisted during the last 3 months. Histologically, all specimens taken from the left nasal cavity, the left submandibular mass and the left upper jugular lymph node showed heavy infiltration of plasma cells, lymphocytes and sheets of macrophages with abundant pale cytoplasm which replaced the existing organ architecture.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Células Plasmáticas
/
Glándulas Salivales
/
Linfocitos
/
Proteínas S100
/
Histiocitosis
/
Histiocitosis Sinusal
/
Obstrucción Nasal
/
Citoplasma
/
Cabeza
/
Ganglios Linfáticos
Límite:
Adolescente
/
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Otolaryngology - Head and Neck Surgery
Año:
2000
Tipo del documento:
Artículo
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