Immunosuppressed model for experimental mice by cyclophosphamid

ABSTRACT

Study on white mices with age of 6-8 weeks, 18-20g body weight. They were divided into 3 groups group 1 (control group) 30 mices; group 2 mices were immunesuppressed by 200mg cyclophosphamid per one kilogram of body weight, being checked after 5 days of injection; and 300mg cyclophosphamid per one kilogram (200mg on the first day and 100mg on the fifth day) and it was checked after 10 days of injection (group 3). The results: immunesuppressed model implemented by intraperitonial injection of 200mg per one kilogram of body weight checked after 5 days of injeciton. These parameters were used to assign the immune function