Usefulness of Intraoperative Parathyroid Hormone Assay in Minimally Invasive Surgery / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
;
: 426-430, 2009.
Artículo
en Coreano
| WPRIM
| ID: wpr-647135
ABSTRACT
BACKGROUND AND OBJECTIVES:
Intraoperative parathyroid hormone (PTH) assay has been proposed as an effective tool in minimally invasive parathyroidectomy. We evaluated its usefulness during minimally invasive parathyroidectomy. SUBJECTS ANDMETHOD:
Ten patients (female 6, male 4) of primary hyperparathyroidism (8 single diseases, 2 multiple diseases) were analyzed retrospectively. We used computed tomography (CT) and 99mTc-Sestamibi (MIBI) scan for localization of parathyroid lesions preoperatively, and frozen biopsy and PTH assay at 10 (T-10), 20 (T-20) minutes after excision intraoperatively. We also compared the diagnostic sensitivity of CT and MIBI scan and intraoperative PTH.RESULTS:
All patients were treated successfully and in single disease group, diagnostic sensitivity of CT, MIBI scan were 75% and 87.5%, and that of T-10 was 75% and T-20 was 100%. In multiple disease group, diagnostic sensitivity of CT, MIBI scan were 75%, 87.5%, and that of PTH was 80%.CONCLUSION:
Intraoperative PTH assay improves cure rate in minimally invasive parathyroidectomy. It allowed intraoperative recognition of missed parathyroid lesions by preoperative imaging study.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Hormona Paratiroidea
/
Biopsia
/
Estudios Retrospectivos
/
Paratiroidectomía
/
Tecnecio Tc 99m Sestamibi
/
Hiperparatiroidismo Primario
Tipo de estudio:
Estudio observacional
Límite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Otolaryngology - Head and Neck Surgery
Año:
2009
Tipo del documento:
Artículo
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