The Comparision of the Radiofrequency Ablasion Therapy with Vertebroplasty and Radiotherapy in Metastatic Spine Tumor / 대한정형외과학회잡지

ABSTRACT

PURPOSE: To evaluation the availability of combined treatment with radiofrequency (RF) ablation with vertebroplasty in patients with metastatic spine tumor. MATERIALS AND METHODS: Between March 2007 and March 2009, 34 patients with the metastatic spine tumor, RF ablation with vertebroplasty was performed in 17 patients, and radiotherapy in the other 17 patients. Cumulative 1-year patient survival rate were compared with the both groups. Pain relief and quality of life were evaluated with use of the visual analogue scale (VAS) and Roland Moris Questionnaire (RMQ). RESULTS: Nine of 17 patients with the RF ablasion therapy with vertebroplasty and 8 of 17 patients with radiotherapy were died. Tumor necrosis was observed in 61.2+/-22.4% (range 28-100%) of the tumor volume. In terms of pain relief, VAS score of preoperative, 1 week and 4 weeks following were 7.12, 3.82 and 3.65 in RF ablation with vertebroplasty group, and 7.00, 5.39 and 4.94 in radiotherapy group(p-value <0.001, <0.001). The score of RMQ score was improved from 12.94 to 7.18 in operation group (p-value <0.001), and 14.11 to 10.89 in radiotherapy group(p-value 0.001). But in terms of pain relief (score of VAS) and quality of life (score of RMQ), RF with vertebroplasty group showed significantly better than the radiotheray group (VAS, p for intercation 0.004, RMQ, p for interaction 0.024). CONCLUSION: RF with vertebroplasty is thought to be a useful method to improve the pain relief and quality of life in patients with metastatic spine tumor.