A Case of Wegener's Granulomatosis Presenting as Facial Paralysis and Hearing Loss / 대한이비인후과학회지

ABSTRACT

Wegener's granulomatosis is a multi-system disease characterized by granuloma formation and necrotizing vasculitis. It classically presents with involvement of the upper, lower respiratory tracts and the renal system. However, locoregional disease is common and may include otological manifestations. In the past, it was fatal if untreated, with a mean survival rate of five months. Recently, because the diagnosis of this disease can be made earlier by measurement of the erythroctye sedimentation rate (ESR) and cytoplasmic anti-neutrophil cytoplasmic antibody (cANCA), the results of treatment have improved. This is a case report of Wegener's granulomatosis in an old woman who had bilateral hearing loss and left facial paralysis, and progressed to acute renal failure due to delayed diagnosis and treatment.