Pathologic Findings of Otosclerosis in Korea / 대한이비인후과학회지

ABSTRACT

BACKGROUND AND OBJECTIVES: Otosclerosis is known to be rare in orientals, but there have been a few reports of the clinically suspicious otosclerosis cases in Korea. Confirmation of otosclerosis, in theory, should be done by histopathology. However, for LASER stapedotomy, it is very hard to obtain the tissue to conduct such histopathological study. In this research, we had surgical specimens available for a review of otosclerosis case. We aimed to confirm the pathologic findings of otosclerosis in Koreans, and review their clinical information. SUBJECTS AND METHOD: Among 126 otosclerosis patients who were operated in the Seoul National University Hospital from January 1981 to December 2001, three cases were selected for pathologic evaluation. We used the H & E method for staining. RESULTS: There were positive histologic findings in all three cases. Two typical phases (early spongiotic and late sclerotic of otosclerosis) could be observed in specimen. CONCLUSION: In the pathologic specimen from the patients showing progressive conductive hearing loss, we could confirm otosclerosis. Both early and late phase of otsclerotic foci coexisted in the same specimen.