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Diagnosis of Cervical Tuberculous Lymphadenitis / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery ; : 263-267, 2002.
Artículo en Coreano | WPRIM | ID: wpr-653392
ABSTRACT
BACKGROUND AND

OBJECTIVES:

Although the incidence of tuberculosis has decreased recently, cervical tuberculous lymphadenitis is one of the most common causes of neck mass in Korea. Its confirmative diagnosis is not common, especially when the presence of acid-bacilli is not proven. So, the treatment of cervical tuberculous lymphadenitis is generally carried out by clinical diagnosis, not by confirmative diagnosis. In this study, we designed to verify theusefulness of fine needle aspiration cytology (FNAC), AFB stain, Mycobacterium tuberculosis polymerase chain reaction (PCR) and excisional biopsy prospectively. MATERIALS AND

METHODS:

We underwent FNAC, AFB stain and PCR as a first stage work-up through fine needle aspiration in forty-eight patients who were suspected of cervical tuberculous lymphadenits. In patients with positive results on the first stage work-up, we treated the patients with antituberculosis chemotherapy under clinical diagnosis of tuberculosis. In patients with negative test results, we performed excisional biopsy. Also in patients who revealed positive results with no response to the antituberculosis chemotherapy, we performed an excisional biopsy too.

RESULTS:

The sensitivity and specificity of first stage work-up were 64.9% and 81.8%, respectively. The sensitivity of FNAC, AFB stain and PCR were 8.1%, 13.5% and 56.8 %, respectively. The specificity of PCR was 81.8%. Thirteen (59.1%) of 22 patients who revealed negative results in their first stage work-up were proven to have cervical tuberculous lymphadentis through excisional biopsy, and two of the positive results in PCR were false positive.

CONCLUSION:

In clinical diagnosis of cervical tuberculous lymphadentis, the first stage work-up used in this study is found to be useful methods which resulted 64.9% sensitivity and 81.8% specificity. Especially, PCR is the most useful tool among them and suggest that, if its result is negative, excisional biopsy should be considered positively.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Tuberculosis / Tuberculosis Ganglionar / Biopsia / Reacción en Cadena de la Polimerasa / Incidencia / Estudios Prospectivos / Sensibilidad y Especificidad / Biopsia con Aguja Fina / Diagnóstico / Quimioterapia Tipo de estudio: Estudio diagnóstico / Estudio de incidencia / Estudio observacional / Estudio pronóstico Límite: Humanos País/Región como asunto: Asia Idioma: Coreano Revista: Korean Journal of Otolaryngology - Head and Neck Surgery Año: 2002 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Tuberculosis / Tuberculosis Ganglionar / Biopsia / Reacción en Cadena de la Polimerasa / Incidencia / Estudios Prospectivos / Sensibilidad y Especificidad / Biopsia con Aguja Fina / Diagnóstico / Quimioterapia Tipo de estudio: Estudio diagnóstico / Estudio de incidencia / Estudio observacional / Estudio pronóstico Límite: Humanos País/Región como asunto: Asia Idioma: Coreano Revista: Korean Journal of Otolaryngology - Head and Neck Surgery Año: 2002 Tipo del documento: Artículo