A Case Report of Castleman's Disease(Giant Lymph Node Hyperplasia) Presenting as a Isolated Neck Mass / 대한이비인후과학회지

ABSTRACT

Castleman's disease, a benign lymphoproliferative disease of unknown etiology, rarely occures as a neck mass. Only 6% of the cases reported in the literature was detected primarily in the neck. This disease consists of unicentric or multicentric (or systemic) forms by clinical manifestation and hyaline vascular type or plasma cell type, histologically. The more common hyaline vascular type usually presents as an asymptomatic lymphoid mass. On the other hand, in plasma cell type, systemic manifestations are frequently observed. Definite diagnosis and treatment is possible with complete surgical resection following histologic evaluation. Recently, we experienced a 22 year old woman patient with 5 year history of right neck mass. She underwent surgical mass resection. Pathologic analysis confirmed hyaline vascular variant of Castleman's disease. Now, we report this case with a review of previously reported literature.