Two Cases of Malignant Melanoma with Nodal Metastasis from Unknown Primary Site / 대한이비인후과학회지

ABSTRACT

About 1% of malignant melanoma is found in the head and neck region and among them, about 2-16% is presented with palpable regional metastatic melanoma with unknown primary lesion (MUP). We have experienced two cases of MUP which were diagnosed after excisional biopsy. MUP has better prognosis than that with known primary lesion. To get good prognosis, the initial treatment of MUP should be regional lymphadenectomy, indicating the importance of an accurate diagnosis. Although the radiologic finding for malignant melanoma may offer no specific findings, physicians should be aware of the possibility of melanoma in neck mass patients. We present two cases of MUP with a literature review.