Clinical efficacy of entecavir in the treatment of hepatitis B cirrhosis complicated with hepatic diabetes / 中国生化药物杂志
Chinese Journal of Biochemical Pharmaceutics
; (6): 213-214, 2017.
Article
en Zh
| WPRIM
| ID: wpr-657541
Biblioteca responsable:
WPRO
ABSTRACT
Objective To investigate the clinical efficacy of entecavir in the treatment of hepatitis B cirrhosis associated with hepatic diabetes. Methods 78 cases of hepatitis B Hepatic Cirrhosis with diabetes were selectedfrom June 2015 to December 2016, and randomly divided into study group (n=39) and control group (n=39). The study group were treated with entecavir, the control group were treated with adefovir dipivoxil. Two groups of patients with hepatitis B cirrhosis combined with hepatic diabetes were treated continuously for 48 weeks, the changes of FPG, HOMA-β, beta and HOMA-IR were recorded. Results There was no significant difference between the two groups in the treatment of FPG, HOMA-β, and HOMA-IR. After treatment, the two groups of FPG and HOMA-IR decreased significantly compared with before treatment, while HOMA-β was significantly higher than before treatment, but the changes of the above indexes in the study group were better than those in the control group (P<0.05). Conclusion Entecavir combined with hypoglycemic agents can achieve more ideal blood glucose control effect in patients with hepatitis B cirrhosis combined with hepatic diabetes..
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Idioma:
Zh
Revista:
Chinese Journal of Biochemical Pharmaceutics
Año:
2017
Tipo del documento:
Article