Abdominal and Pericardial Fat in Patients with and without Coronary Artery Disease: Computed Tomography Study
Journal of Lipid and Atherosclerosis
;
: 29-37, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-65822
ABSTRACT
OBJECTIVE:
There has been a limited investigation looking into the correlation between pericardial fat and abdominal fat with coronary artery disease (CAD) as measured by coronary computed tomographic angiography (CCTA). We proposed that the volume of pericardial fat is larger in patients with CAD than in patients without CAD, and sought to determine which abdominal adiposity index best correlated with pericardial fat volume.METHODS:
Participants were examined using CCTA between October 2007 and January 2008. All participants had no previous history of CAD. Pericardial adipose tissue (PAT) volume, abdominal total adipose tissue volume, abdominal subcutaneous adipose tissue volume, and abdominal visceral adipose tissue (AVAT) volume were measured using CCTA.RESULTS:
Fifty patients (26.5%) demonstrated CAD, and 139 patients did not demonstrate CAD by CCTA. PAT volume in patients with CAD was larger than that of patients without CAD (173.2+/-64.2 cm3 vs. 147.6+/-50.4 cm3, p<0.01). However, indices of abdominal adiposity were not significantly different between the two groups. Using multivariable analysis, independent predictors of CAD were PAT volume (odds ratio [OR] 1.01, 95% confidence interval [CI] 1.00-1.02, p=0.04), coronary artery calcium score (OR 1.01, 95% CI 1.00-1.01, p<0.01), and typical chest pain (OR 4.88, 95% CI 1.47-16.21, p=0.01). AVAT volume showed a linear correlation with PAT volume.CONCLUSION:
PAT volume was an independent predictor of CAD as measured by CCTA. PAT volume was also well correlated with the AVAT volume among the indices of abdominal adiposity.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Dolor en el Pecho
/
Enfermedad de la Arteria Coronaria
/
Angiografía
/
Tejido Adiposo
/
Calcio
/
Vasos Coronarios
/
Grasa Abdominal
/
Grasa Intraabdominal
/
Grasa Subcutánea Abdominal
/
Adiposidad
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Journal of Lipid and Atherosclerosis
Año:
2014
Tipo del documento:
Artículo
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