Advances in Study on Role of Circular RNA in Digestive System Neoplasms / 胃肠病学

ABSTRACT

Circular RNA (circRNA),a class of non-coding RNA (ncRNA),widely exists in various kinds of cells. CircRNA is highly conserved in different species and can act as a miRNA sponge to regulate gene expression. More and more studies showed that circRNA plays an important role in pathogenesis and development of digestive system neoplasms, and can be used as a biomarker for diagnosis and prediction of prognosis. However,its function still needs further research to verify. This article reviewed the advances in study on role of circRNA in digestive system neoplasms.