Efficacy and safety of domestic esomeprazole in the treatment of peptic ulcer bleeding / 中国生化药物杂志

ABSTRACT

Objective To analyze the safety and efficacy of domestic esomeprazole injection in treating peptic ulcer bleeding. Methods A total of 98 patients with peptic ulcer bleeding were enrolled in Zhejiang Xiaoshan hospital from January 2016 to December 2016 were divided into the observation group and the control group by random number table. Both groups were given the same routine treatment, the observation group was given domestic esomeprazole injection on the basis treatment, the control group was given imported eschenopramine injection, clinical efficacy and safety of two groups were compared. Results There was no significant difference in the effective rate of treatment, the total efficacy and adverse reactions between two groups, but the cost in the observation group was significantly lower than that of the control group (P<0.05). Conclusion For the treatment of peptic ulcer bleeding, both of domestic and imported eschenopramine injection treatment could be received more satisfactory clinical efficacy, but the cost of domestic esomeprazole injection is lower than that of imported esomeprazole..