Determination of accessories lactose by HPLC-RID / 药物评价研究
Drug Evaluation Research
;
(6): 942-945, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-660886
ABSTRACT
Objective To establish a method for determination of accessories lactose by HPLC-RID.Methods Boston Green Amino-NH2 column (250 mm× 4.6 mm,5 μm) was used.The mobile phase was acetonitrile-water (7030).The flow rate was 1.0 mL/min.The column temperature was 45 ℃,the detector temperature was 40 ℃ and the injection volume was 10 μL.Results Lactose showed good linearity in the range of 0.2-5.0 mg/mL (r≥0.999 8).The detection limit was 0.06 mg/mL.The average recovery was 99.6% and the relative standard deviation was 0.7%.Conlusion The method is specific,convenient,fast and accurate,which can be used for determination of accessories lactose.
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Drug Evaluation Research
Año:
2017
Tipo del documento:
Artículo
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