Effects of extreme dose of heat-clearing drugs on the temperature of the patients with postoperative fever / 国际中医中药杂志

ABSTRACT

Objective To observe the effect of exteme dose of heat-clearing drugs on temperature in the postoperative fever patients.Methods A total of 70 patients with postoperative fever who met the inclusion criteria were randomly divided into the control group (35 patients) and observation group (35 patients). The observation group was treated with exteme dose of heat-clearing drugs, and the control group was treated with the common dose formula. Both groups were treated for 3 day, and followed up for 3 day. The changing of the temperature before and after treatment, the onset time and time of relieving fever were analyzed.Results Compared with the baseline before the treatment, the 1st day, 2nd after treatment, the highest temperature in observation group at thte 3rd day(37.5 ± 0.5℃vs. 37.6 ± 0.5℃, 38.1 ± 0.5℃,38.3 ± 0.5℃,F=20.883) was significantly lower; the highest body temperature in the control group at the 3rd day (37.5 ± 0.6℃vs. 37.5 ± 0.5℃, 38.1 ± 0.6℃, 38.4 ± 0.4℃,F=25.088) was significantly lower (P<0.01). At the 3 day in the follow up period, compared with the baseline before the treatment, the 1st day, 2nd after treatment, the highest body temperature in observation group (36.9 ± 0.5℃vs. 37.1 ± 0.2℃, 37.3 ± 0.5℃,F=7.778) were significantly lower (P<0.01).Conclusions The high of heat-clearing drugs treatment for the postoperative fever can effectively lower the temperature, and there is no obvious difference of the onset time and the time of relieving fever between two groups.