Molecular and Epidemiological Characterization of Carbapenem-Resistant Acinetobacter baumannii in Non-Tertiary Korean Hospitals
Yonsei Medical Journal
;
: 177-182, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-66224
ABSTRACT
PURPOSE:
The increasing prevalence and global spread of carbapenem-resistant Acinetobacter baumannii (A. baumannii) has become a serious problem. The aim of this study was to investigate molecular and epidemiological characteristics of carbapenem-resistant A. baumannii isolates collected from Korean non-tertiary hospitals. MATERIALS ANDMETHODS:
Thirty six non-duplicated carbapenem-resistant A. baumannii isolates were collected from 17 non-tertiary hospitals in Korea between 2004 and 2006. Isolates were typed by multilocus sequence typing and repetitive-sequence-based PCR (rep-PCR). Detection of genes encoding OXA carbapenemase and their relationship with ISAba1 was performed by PCR.RESULTS:
Two clones were prevalent among 36 isolates ST69 (17 isolates, 47.2%) and ST92 (19 isolates, 52.8%). Rep-PCR patterns were diverse and revealed that all isolates were clustered into eight band patterns. The ISAba1-activated blaOXA-23-like and ISAba1-activated blaOXA-51-like genes were prevalent among the carbapenem-resistant A. baumannii isolates.CONCLUSION:
The class D beta-lactamase genes of A. baumannii were distributed nationwide in non-tertiary Korean hospitals.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Beta-Lactamasas
/
Infecciones por Acinetobacter
/
ADN Bacteriano
/
Pruebas de Sensibilidad Microbiana
/
Carbapenémicos
/
Reacción en Cadena de la Polimerasa
/
Prevalencia
/
Técnicas de Tipificación Bacteriana
/
Epidemiología Molecular
/
Farmacorresistencia Bacteriana
Tipo de estudio:
Estudio de prevalencia
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Yonsei Medical Journal
Año:
2013
Tipo del documento:
Artículo
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