Depressor Substances Test and Histamine Test for the Quality Control of Deproteinized Culf Blood Extrac-tives Injection / 中国药师
China Pharmacist
;
(12): 2264-2266, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-664086
ABSTRACT
Objective:
To explore the applicability of depressor substances test and histamine test for the quality control of depro-teinized culf blood extractives injection.Methods:
Depressor substances test and histamine test were carried out on 10 batches of deproteinized culf blood extractives injection samples.Results:
Some samples showed positive reactions in the experiments. The correl-ative analysis showed positive correlation existed between the results of depressor substances test and histamine test. However, part of samples causing blood pressure decrease in anesthetized cats showed negative or relatively reduced results in histamine test. Conclu-sionDeproteinized culf blood extractives injection may be contaminated by depressor substances. Part of these substances may not be histamine analogue, therefore, depressor substances test may be considered in the quality control of the product.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
China Pharmacist
Año:
2017
Tipo del documento:
Artículo
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