Ultrasonic observation on carotid plaques in patients with acute ischemic stroke / 中国介入影像与治疗学

ABSTRACT

Objective To investigate distribution of carotid plaques,degree of stenosis and risk factors of unstable plaques in patients with acute ischemic stroke.Methods Totally 909 patients with acute ischemic stroke (AIS group) confirmed with head MRI were enrolled,while 885 patients without stroke in the same period hospitalization were selected as controls (control group).The distribution of carotid plaques and the degree of stenosis were compared between the 2 groups.Patients in AIS group were divided into stenosis rate ≥50％ subgroup and ＜50％ subgroup according to the degree of carotid artery stenosis,and the detectable rate of stable plaques and unstable plaques were compared between the 2 groups.Clinical data of patients with unstable plaques and non-unstable plaques in AIS group were compared.Logistic regression models were established with parameters with significantly differences among those features.Results The detectable rates of multiple plaques and unstable plaques of carotid artery and the degree of stenosis in AIS group were statistically higher than those in control group (all P＜0.001).The detectable rate of unstable plaque in carotid artery stenosis rate ≥50％ group was statistically higher than that in stenosis rate ＜50％ group (P＜0.001).Age,male,diabetes,dyslipidemia,smoking and drinking were significantly risk factors (all P＜0.05).Age,diabetes,dyslipidemia and smoking were independent risk factors (all P＜0.05).Conclusion Carotid unstable plaque and stenosis are closely related to the occurrence of AIS.Age,diabetes,dyslipidemia and smoking are independent risk factors for carotid artery plaque.