Advances in Study on Novel Biological Agents in Treatment of Inflammatory Bowel Disease / 胃肠病学

ABSTRACT

Inflammatory bowel disease (IBD) is a chronic,non-specific intestinal inflammatory disease.Traditional drug therapy includes aminosalicylates,glucocorticoids and immunosuppressive agents,and their long-term use will induce multiple side effects,and having high recurrence rate and poor efficacy in critically ill patients.Studies have shown that biological agents are effective in inducing and maintaining remission in patients with IBD,promoting mucosal healing,and improving the quality of life.With the in-depth study of pathogenesis of IBD,researches on the development of novel biological agents have been performed widespreadly.This article reviewed the advances in study on novel biological agents in treatment of IBD.