Retrospective analysis of special type endometrial cancer cases in Peking Union Medical College Hospital during 2005-2010 / 基础医学与临床

ABSTRACT

Objective To estimate outcome and prognostic risk factors of special type endometrial cancer .Methods Clinic data was collected in Peking Union Medical College Hospital during 2005-2010 .SPSS software was used to analyze data .Logistic regression analysis was used to analyze prognostic risk factors respectively .Results Medium follow up time of total 48 endometrial serous carcinoma , clear cell carcinoma and carcinosarcoma patients was 70.5 months.Most of patients could be diagnosed at early time ( FIGO stage Ⅰand stage Ⅱwere 66.7%among all pa-tients) .The main treatment was operation and followed by chemo-therapy and radio-therapy.66.7%of patients ac-cepted chemo-therapy after operation , and 41.7%of patients accepted radio-therapy .The outcome of advanced pa-tients was poor.30.8%stage Ⅲrelapsed and died in 3 years.The recurrence rate and mortality of stage Ⅳwere all 100%.The recurrence rate of advance endometrial serous carcinoma was 80%, which was much higher than the other two.FIGO stage and lymphatic metastasis were the main prognostic risk factors .Conclusions Special type of endometric cancer has a poor prognosis and lymphatic metastasis is main reason to explain the prognosis .