Protective effect and its molecular mechanism of dexmedetomidine on nerve injury / 中国医师进修杂志

ABSTRACT

Dexmedetomidine (DEX) is a specific α2 receptor agonist, which has high analgesic and neuroprotective effects on the basis of less side effects.Due to the advantages of DEX,it is currently used in ICU,anesthesia and other fields.In recent years,its neuroprotective effect has attracted extensive attention.It has been reported that DEX plays a critical role in the injured development brain, postoperative cognitive dysfunction (POCD) and other diseases.The specific mechanism is unknown, which needs to be further explored.