Biological characteristics and lymph node metastasis in papillary thyroid microcarcinoma / 中华普通外科杂志
Chinese Journal of General Surgery
;
(12): 858-862, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-666812
ABSTRACT
Objective To determine the correlation between biological characteristics and neck lymph node metastasis in papillary thyroid microcarcinoma (PTMC).Methods Clinical biological data were collected from patients first diagnosed with PTMC at the Xinjiang Medical University Affiliated Tumor Hospital from January 2010 to March 2016.Chi-square test and multivariate logistic regression analysis were used to identify risk factors of neck lymph node metastasis.Results With regard to clinical biological features of patients with PTMC,the male to female ratio is 1 ∶ 4.4.TNM stage Ⅰ accounted for 81.6% in 1 622 cases,stage Ⅲ in 285(14.3%),stage ⅣA in 78(3.9%),stage ⅣB in 1 (0.05%),stage ⅣC in 2(0.1%) patients.All in all,34.9% patients had the neck central lymph node metastasis.Multivariate logistic regression analysis indicated that age at diagnosis <45 years (P <0.001,OR =0.602),maleness (P < 0.001,OR =0.473),tumor number≥3 (P =0.008,OR =1.843),tumor size > 5 mm (P < 0.001,OR =2.571),capsular invasion (P =0.035,OR =1.571),extrathyroidal extension (P =0.005,OR =1.834) were independently correlated with the neck lymph node metastasis.Conclusions An increased risk of the neck lymph node metastasis are seen in PTMC patients with male gender,age < 45 years,tumor number ≥3,tumor size > 5 mm,capsular invasion and extrathyroidal extension.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
/
Factores de riesgo
Idioma:
Chino
Revista:
Chinese Journal of General Surgery
Año:
2017
Tipo del documento:
Artículo
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