New topic of complement and diseases / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
;
(12): 643-647, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-668112
ABSTRACT
Complement system is involved in the pathogenesis of a group of diseases and also provides an important interface between the innate and adaptive immune response.Currently available tools provide an exciting opportunity to study this system,and some diseases were found to be resulted from excessive and uncontrolled activation of the complement of which the pathogenesis used to be unclear,such as paroxysmal nocturnal hemoglobinuria (PNH),atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G),etc.Several complement inhibitors have been approved for clinical use,and additional complement inhibitory drugs are in development.The use of these drugs in patients will expand our understanding of the benefits and limitations of complement inhibition in human diseases.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Laboratory Medicine
Año:
2017
Tipo del documento:
Artículo
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