Use of Noninvasive Hemodynamic System to Monitor the Hemodynamic Effects Caused by Oxytocin Used in Cesarean Section / 中国医科大学学报

ABSTRACT

Objective To investigate noninvasive hemodynamic system in monitoring the hemodynamic trends caused by oxytocin and key time points during cesarean section.Methods Forty pregnant women who tmderwent an elective caesarean section were included in this study.We administered 10 U oxytocin via intravenous infusion at 5 U/h and 10 U into the Murphy's dropper after fetal delivery.Systolic blood pressure (SBP),diastolic blood pressure (DBP),mean arterial pressure (MAP),and heart rate (HR) were measured immediately,and every 10 seconds in the following 180 seconds.All 40 pregnant women were monitored using the noninvasive hemodynamics system.In 20 of these women,simultaneous measurements of invasive blood pressure (IBP) were performed at the same time.Results SBP,DBP,and MAP declined at 20 seconds after oxytocin was administered and reached their minimum values at 50 to 60 seconds.The values returned to normal at 120 seconds (P＜ 0.05),with statistically significant differences (P ＜ 0.05).HR started to increase at 30 seconds,peaked at 60 seconds,and returned to normal at 100 seconds (P ＜0.05),with statistically significant differences (P ＜ 0.05).However,no statistically significant differences in SBP,DBP,and HR were observed between the invasive and noninvasive hemodynamic systems (P ＞ 0.05).Conclusion Application of 10 U of intravenous oxytocin and 10 U oxytocin infusion led to the most significant hemodynamic change within 60 seconds.SBP,DBP,MAP,and HR returned to normal within a short time (120 seconds),without special treatment.