High-affinity glutamate transporters and chronic pain / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1094-1099, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-669340
ABSTRACT
Glutamate serves as a major excitatory neurotransmitter in the mammalian central nervous system and is stored in synaptic deft by an uptake system that is dependent on the high-affinity glutamate transporters (ETTAs),which locate in the plasma membrane of glial cells and neurons.ETTAs can rapidly terminate the action of glutamate and maintain its normal physiological functions.If the content or function of glutamate transporters is abnormal,it can result in many physiological dysfunctions.Studies have demonstrated that high-affinity glutamate transporters play an important role in the development of chronic pain,which might be a new therapeutic target for the pain.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Central South University(Medical Sciences)
Año:
2017
Tipo del documento:
Artículo
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