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Economic Evaluation of rhIL-11 (Ⅰ) and rhTPO in the Treatment of Thrombocytopenia Caused by Chemotherapy / 中国药师
China Pharmacist ; (12): 250-252, 2015.
Artículo en Chino | WPRIM | ID: wpr-669703
ABSTRACT

Objective:

To evaluate the efficacy and pharmacoeconomics of rhIL-11(Ⅰ) and rhTPO in the treatment of thrombocy-topenia caused by gemcitabine chemotherapy in lung cancer patients.

Methods:

A retrospective analysis was used. Totally 58 hospital-ized lung cancer patients who suffered thrombocytopenia caused by gemcitabine chemotherapy and treated with rhIL-11(Ⅰ) or rhTPO from June 2011 to June 2014 were involved in the study, and the efficacy and pharmacoeconomics of rhIL-11(Ⅰ) and rhTPO were e-valuated and compared.

Results:

The lowest platelet value after the chemotherapy in rhIL-11(Ⅰ) group was higher than that in rhTPO group (P0. 05). The results of cost-minimization anal-ysis showed that the average cost of rhIL-11(Ⅰ) group was lower than that of rhTPO group(P<0. 01), furthermore, the average cost of the patients with GP, GC or the other gemcitabine chemotherapy regimens in rhIL-11 (Ⅰ) group was lower than that in rhTPO group.

Conclusion:

The effect of rhIL-11 (Ⅰ) in the treatment of thrombocytopenia caused by gemcitabine based-chemotherapy in lung cancer patients is not inferior to that of rhTPO, and shows certain advantages in economic cost.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Evaluación Económica en Salud Idioma: Chino Revista: China Pharmacist Año: 2015 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Evaluación Económica en Salud Idioma: Chino Revista: China Pharmacist Año: 2015 Tipo del documento: Artículo