HPV infection,overexpression of P53 and Ki-67 protein in oral warts from HIV-positive patients / 实用口腔医学杂志
Journal of Practical Stomatology
; (6)2000.
Article
en Zh
| WPRIM
| ID: wpr-670709
Biblioteca responsable:
WPRO
ABSTRACT
Objective: To detect P53 and Ki-67 protein,human papill om a virus (HPV),cytomegalovirus(CMV) and Epstein-Barr virus(EBV)in the warts of o ral mucosa from HIV-positive patients.Methods: The expression P53 and Ki-67 protein,HPV,EBV and CMV were detected by immunohistochemistry and PCR in 34 cases of oral mucosa warts from HIV-positve patients,33 cases of oral epithelia dysplasia and 45 cases of oral squamous cell carcinoma. Results:(1)The expression of P53 and Ki-67 protein in the cases of oral mucosa warts from HIV-positive patients were 23%and 76% re spectively,lower than those in oral suquamous cell carcinoma lesions from non- HIV individuals(62.8% and 97.8% respectively,P0.05).(2)The HPV infection in the warts of oral mucosa from HIV -positive patients was 88.2%,much higher than in oral suquamous cell carcinoma lesions (35.6%) and in dysplastic lesions (9.1%) from non-HIV individuals(P
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Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Practical Stomatology
Año:
2000
Tipo del documento:
Article