Transforming growth factor ?1 induces apoptosis in mouse odontoblast cell line MDPC-23 / 实用口腔医学杂志
Journal of Practical Stomatology
; (6)1995.
Article
en Zh
| WPRIM
| ID: wpr-670750
Biblioteca responsable:
WPRO
ABSTRACT
Objective:To investigate if transforming growth factor-?1 (TGF-?1) induces apoptosis in odontoblast cell line MDPC-23. Methods:MDPC-23 cells were treated with TGF-?1 at 0.5,2.5 or 10 ng/ml for 48 h,apoptosis of MDPC-23 cells was detected by annexin V and propidium iodide (PI) staining, cell death detection ELISA and DNA electrophoretic analysis. Results: Consistent results were obtained from three different methods.TGF-?1 at 0.5-10 ng/ml induced apoptosis of MDPC-23 cells in a dose-dependent manner. Conclusion:TGF-?1 may paly a role in apoptosis of odontoblasts.
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WPRIM
Idioma:
Zh
Revista:
Journal of Practical Stomatology
Año:
1995
Tipo del documento:
Article