A case-control study on periodontal status between pre-term and full- term / 实用口腔医学杂志

ABSTRACT

Objective: To compare the difference of maternal periodontal status and TNF-? levels in gingival cervical fluid in pregnancy with pre-term and full-term and find the relationship between periodontal infections and pre-term. Methods:The case group consisted of 28 women with pre-term and the control group consisted of 22 women giving birth in time. The clinical examination was performed before delivery. The periodontal conditions were evaluated on the basis of the following parameters gingival index(GI), probing depths(PD), clinical attachment level(CAL) and sulcus bleeding index(SBI). Gingival crevicular fliud(GCF) samples were collected from all individuals and TNF-? levels were measured by enzyme-linked immunoabsorbent assay. Results:Clinical periodontal measures(GI, PD, CAL, SBI) in pre- term group were significantly greater than that in the control group. And pre- term group also showed higher prevalence of periodontitis. TNF-? in GCF was detected in 67.85% of pre-term group and in 27.27% of the control group. GCF volumes of case group significantly increased than that of control group. Significant negative correlations were observed between the gestational age at delivery and PD as well as GCF- volumes. Conclusion: There is a possible link between periodontal infections and pregnancy with pre-term condition.