Chinical research on the perioperative application of propranolol in patients with hyperthyroidism / 中国普通外科杂志

ABSTRACT

Objective To investigate the effects of propranolol on thyroid hormone in patients with hyperthyroidism after operation. Methods Forty patients with mediate or severe degree hyperthyroidism undergoing operation were randomly divided into four groups according to anesthesia and whether to take propranolol in perioperative period Group Apropranolol plus general anesthesia; Group B general anesthesia; Group Cpropranolol plus cervical plexus blocking; Group D cervical plexus blocking. The consecutive changes of T 3, T 4,rT 3 and TSH were measured with radioimmunological assay pre and post operatively. Results The level of serum T 3 in all groups decreased 1～7 days after operation. The decrease in serum T 3 leves was most significant 3～7 days after operation in group A and C, 1～3 days after operation in proup B and D(P