Predictive Factors for Valproate Treatment in Childhood Absence Epilepsy / 대한소아신경학회지
Journal of the Korean Child Neurology Society
; (4): 7-13, 2010.
Article
en Ko
| WPRIM
| ID: wpr-67409
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: To determine the clinical and demographic factors associated with long-term remission of valproate(VPA) therapy in childhood absence epilepsy. METHODS: Fifty-six cases of childhood and juvenile absence epilepsy were identified by reviewing of Electroencephalographic records and medical charts. Thirty-six cases were initially treated with VPA. Factor associated with responsiveness were identified by uni- and mutivariate logistic regression. RESULTS: Twenty-seven patient achieved long-term remission(75%). Failure to achieve remission was more likely if the initial treatment of VPA had failed than if it was successful(53% versus 90.4%, P<0.02) was also associated with failure of long-term remission. Lamotrigine was more efficacious add-on drug than Ethosuximide(63.6% vs 25% P=0.04). CONCLUSION: Long-term seizure remission was related to the patient's initial response to VPA.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Convulsiones
/
Triazinas
/
Modelos Logísticos
/
Demografía
/
Ácido Valproico
/
Epilepsia Tipo Ausencia
/
Epilepsia
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
Ko
Revista:
Journal of the Korean Child Neurology Society
Año:
2010
Tipo del documento:
Article