Clinical and Experimental Study on Weiling Granule for Treatment of Peptic Ulcer / 中医杂志

ABSTRACT

Objective:To study on effects of Welling Granule on union of peptic ulcer and the gastrical ulcer induced by acetic acid in the rat. Methods:With random grouping method,the clinical recurrence rate of peptic ulcer,and regenerated macosa of healing gastric ulcer in the rat was investigated quantitatively with hematoxylin-eosin staining,and gastric wall combining macus amount,gastric acid and pepsin activity were determined.Results:Weiling Granule could decrease the recurrence rate of peptic ulcer,improve injury of the tissue of gastric macosa in the rat,increase gastric wall combining mucus amount,and decrease secretion of gastric acid.Conclusion:Weiling Granule can increase quality of ulcerative healing,which is possibly one of the mechanisms of anti- recurrence of peptic ulcer clinically.