Analysis of MHC complotype of han nationality chinese in guangdong area / 中国免疫学杂志

ABSTRACT

It was the first time that the complotypes of 84 chromosomes from Han nationality healthyChinese families investigated and analyzed in Guangdong are a with the methods adopted fromthe international complement reference laboratory.The results showed 18 various complolypeswere identified.The precedent complotypes are SC31,SC42,SC32 and SC41.There were 7 com-potypes of them existing the linkage disequilibria.The highest allotypes gene frequencies of thefour loci of complotypes were respectively as follows,BF S for BF alleles,C2C for C2 alleles,C4A3 and C4A4 for C4A alleles,C4B2 and C4B1 for C4B alleles.The C4AQO allele for C4A lo-cus was 4.8% and 1.2%C4BQO alleles for C4B locus.The frequencies of major complolypesfrom the data showed the similarities among Mongolian,Caucasian,Japanese and south easternAsia populations.The significance of the different frepuencies between the complotypes has beendiscussed.