Comparison of 3 Automated Immunoassays for Hepatitis B Surface Antigen / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 282-286, 2006.
Artículo
en Coreano
| WPRIM
| ID: wpr-67550
ABSTRACT
BACKGROUND:
Hepatitis B surface antigen (HBsAg) is one of the most important serological markers used to diagnose hepatitis B virus (HBV) infection. Automated immunoassays have been developed, meeting the current clinical requirement of HBsAg assays over the years. This study was performed to determine the degree of agreements between 3 kinds of HBsAg assay systems.METHODS:
Serum samples from 425 patients were assayed by the HBsAg assay systems of Elecsys (Roche Diagnostics, Germany), ADVIA Centaur (Bayer Diagnostics, USA), and AxSYM (Abbott Laboratories, USA).RESULTS:
The concordance rates among the 3 assays were 100%. A total of 249 (58.6%) specimens were positive, and their index values showed a weak correlation between the 3 assays; nevertheless, positive specimens with low levels (<10) of index values in one system also presented low values in other systems, and all of them were confirmed by neutralization assays.CONCLUSIONS:
The 3 automated HBsAg assay systems presented a high level of concordance.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Inmunoensayo
/
Virus de la Hepatitis B
/
Hepatitis
/
Hepatitis B
/
Antígenos de Superficie de la Hepatitis B
Límite:
Humanos
Idioma:
Coreano
Revista:
The Korean Journal of Laboratory Medicine
Año:
2006
Tipo del documento:
Artículo
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