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Significance of p53 and C-erbB-2 expression in endemic and AIDS-related Kaposi’s sarcoma in Africa / 中国癌症杂志
China Oncology ; (12)2001.
Artículo en Chino | WPRIM | ID: wpr-675506
ABSTRACT

Purpose:

To study the significance of p53 protein, p53mRNA, and C erbB 2 protein expressions in Africa endemic and AIDS related Kaposi's sarcoma (KS).

Methods:

Immunohistochemistry and hybridization in situ were performed with p53 and C erbB 2 in 30 cases with endemic and AIDS related KS.The degree of pasitivity of p53 and C erbB 2 in KS tissues were measured with image analysis system. KS was classified into three types, i.e., angiomatous type, spindle cell type, and mixed type according to the proportion of blood vessel components and spindle cells in the lesions.

Results:

The degree of positivity of p53 protein was stronger in spindle cell type than that in angiomatous type ( P

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: China Oncology Año: 2001 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: China Oncology Año: 2001 Tipo del documento: Artículo