Protective effect of Coixan on panceratic islet ? cell injury by Alloxan in rats / 中国药理学通报

ABSTRACT

0 05);②Coixan(100 mg?kg -1 ) could prevent rats from diabetes induced by alloxan. the blood glucose and the area of curve in the preventive group was lower than in the alloxan group. The activity of superoxide dismutase(SOD) in the preven tive group was higher than in the alloxan group. The morphological observation of ? cells confirmed that coixan could markedly prevent ? cells from injury induced by alloxan and there was no obvious change in the appearance of islet ? cells in the preventive group. CONCLUSION Coixan markedly prevents ? cells from injury induced by alloxan.