Bioactivity and relative bioavailability of domestic salcaltonin injection in Chinese healthy volunteers / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)1987.
Article
en Zh
| WPRIM
| ID: wpr-677288
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WPRO
ABSTRACT
0 05). The main pharmacokinetic parameters are: C max : (2 31?0 16) ?g?L -1 and (2 44?0 20) ?g?L -1 ; T max : (48 75?12 99) min and (52 50?16 31) min; T 1/2ke : (92 93?11 86) min and (97 61?11 23) min; K e: (0 0079?0 0023) min -1 and (0 0084?0 0014) min -1 ; AUC (0~360 min) : (297 70?44 45) ?g?min?L -1 and (313 64?46.03) ?g?min?L -1 respectively in domestic and imported salcaltonin injections. The relative bioavailability of domestic formulation is 97 6%?25 6%. CONCLUSION The domestic and imported salcaltonin injections administered produce similar biological response and bioavailability and they are bioequivalent.
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WPRIM
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Zh
Revista:
Chinese Pharmacological Bulletin
Año:
1987
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Article