Effects of Di-p-Cl-benzoyl-linesinine on experimental arrhythmia / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)1987.
Article
en Zh
| WPRIM
| ID: wpr-678186
Biblioteca responsable:
WPRO
ABSTRACT
AIM The purpose is to study the effect of Di p Cl benzoyl linesinine on experimental arrhythmias. METHODS The models used were caused by aconitine, ouabain and CaCl 2 repectively. RESULTS Di p Cl benzoyl linesinine 5 mg?kg -1 could increase the threshold dose of ventricular ectopic(VE), ventricular tachyacardia(VT), ventricular fibrillation(VF) and cardiac arrest(CA) caused by aconitine in rats and that by ouabain in ginuea pigs; delay the onset time of arrhythmia and decrease the incidence of VE,VF and CA induced by CaCl 2 in rats. CONCLUSION Di p Cl benzoyl linesinine possesses extensive effects of antiarrhythmia on ventricle.
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WPRIM
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Año:
1987
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Article