Indications and contra-indications of antibiotic lock technique in central venous catheter / 肠外与肠内营养

ABSTRACT

Objectives:To study indications and contra indications of antibiotic lock technique in central venous catheter. Methods:Fifty patients with sepsis during use of central venous catheter were studied prospectively.The drug of ceftazidine(0.5 g) was instilled into the central line as a transient “lock”, together with mixed solution(5 ml) of normal saline and heparin sodium. Results:Twenty nine cases were proved to be catheter related sepsis.5 cases were treated by removal of infected catheter.Twenty four cases were treated by antibiotic lock technique.Out of 24,only 13 cases wee successful. Conclusions:Indications of antibiotic lock technique are as follows① transient use when looking for source of infection, ② in patients with late stage tumor, ③inpatients with steady state of illness and ④patients receiving home parenteral nutrition.The contra indications include①inpatients in unsteady state of illness,②for short term transfusion or parenteral nutrition, ③patients with compromised immune responsiveness,and ④with deteriorated state of an illness or the infections not controlled.