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Human telomerase,P53, estrogen and progesterore receptor expression in endometrial carcinoma / 北京大学学报(医学版)
Journal of Peking University(Health Sciences) ; (6)2004.
Artículo en Chino | WPRIM | ID: wpr-678761
ABSTRACT

Objective:

To study the role of hTERT and c myc, P53, ER, PR in endometrial carcinoma carcinogenesis.

Methods:

The expression of hTERT, c myc mRNA, P53 protein, ER and PR examined by in situ hybridization and immunohistochemistry in 14 cases of endometrial simple hyperplasia, 10 of complex hyperplasia, 8 of atypical hyperplasia and 52 with endometrial carcinoma.

Results:

(1) The positve rate of hTERT in simple, complex, atypical hyperlasia and carcinoma were 14.3% (2/14), 50.0% (4/8), 80.0% (8/10) and 92.3% (48/52), respectively. The prevalence and intensity of hTERT signal were greater in the carcinomas and atypical hyperplasia than those in simple or complex hyperplasia (P

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Journal of Peking University(Health Sciences) Año: 2004 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Journal of Peking University(Health Sciences) Año: 2004 Tipo del documento: Artículo