Prescription screening of dispersible compound melatonin tablets / 第三军医大学学报

ABSTRACT

Objective To prepare dispersible compound melatonin tablets which can be quickly effective and used conveniently Methods The effective factors in the ingredients of the dispersible compound melatonin tablets were observed by orthogonal experiment design and the prescription was screened by disintegrating time limit Results The dispersible tablets could disintegrate completely in 50 seconds and the suspension could pass through 710 nm sifter in the dispersing test The dissolution rate could reach 92 9% in 5 minutes Conclusion The dispersible compound melatonin tablets can be prepared conveniently and easily disintegrate and dissolve