ELECTRON MICROSCOPE STUDIES ON THE HISTOCHEMICAL LOCALIZATION OF ATPase AND SUCCINIC DEHYDROGENASE ACTIVITIES IN THE CANCER CELL OF THE MOUSE MAMMARY GLAND / 解剖学报

ABSTRACT

This paper presents the results of the histochemical study on the activities ofATPase and succinic dehydrogenase and their distribution in mammary gland cancercell of mice by means of electron microscopy.It was found that the activity of ATPase activated by Mg~(++)were mainly locatedon the mitochondrial membrane,the nuclear membrane and the nucleolus,and that ofATPase activated by Ca~(++)were located on the cristae and matrix of mitochondria aswell as the outer nuclear membrane,and also evenly distributed in the chromatin.The activity of the succinic dehydrogenase is mainly located on the cristae andthe inner membrane of mitochondria.An alternitive responses of strong and weakactivities of the enzyme were shown between the outer and inner nuclear membranes.In the mean-while,the activity of the succinic dehydrogenase was also shown in ahigh level in the outer cytoplasmic membrane and the inner nuclear membrane.