Induction of rat cerebellar granular neuron apoptosis by 1-methyl-4-phenyl pyridinium cation / 中草药
Chinese Traditional and Herbal Drugs
;
(24)1994.
Artículo
en Chino
| WPRIM
| ID: wpr-681240
ABSTRACT
Object To establish a rat cerebellar granular neuron (CGN) apoptosis model by 1 methy 4 phenyl pyridinium cation (MPP +) Methods Rat CGN were treated with MPP + and the resulting cell morphology examined by methyl green pyronine staining, agarose gel electrophorsis of DNA and flow cytometry Results MPP + at the concentration of 50 ? mol/L can induce CGNs apoptosis of the established model Conclusion The CGNs apoptosis model induced by MPP + can be used for the study on regulatory mechanism of cell apoptosis and the screening of antiparkinsonian drugs
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Traditional and Herbal Drugs
Año:
1994
Tipo del documento:
Artículo
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