Antioxidant Effects of Munziq and Mushil of Abnormal Savda by Electron Paramagnetic Resonance / 中药新药与临床药理

ABSTRACT

To explore the antioxidant mechanism of munziq and mushil of Abnormal Savda. Scavenging effects of munziq and mushil of Abnormal Savda on superoxide anion radical(O -? 2) and hydroxyl radical (OH ?) were measured by electron paramagnetic resonance(EPR). Munziq and mushil possessed obvious scavenging effects on O -? 2 and OH ? and the effect of mushil was superior to that of the munziq.[Conclusion] The EPR is a reliable, effective, accurate, sensitive method for measuring the antioxidant properties of herbal medicines. Munziq and mushil are two kinds of effective antioxidants, and the antioxidant effect may be one of the therapeutic mechanisms of munziq and mushil.