Study on microwave-assisted extraction process for active ingredients in Radix acanthopanacis senticosi / 中成药

ABSTRACT

Objective: To study the microwave assisted extraction process for saponins and isofraxidin in Radix Acanthopanacis Senticosi as a marker. Methods: Using the uniform design, the optimization process of microwave assisted extraction for saponins and isofraxidin in Radix Acanthopanacis Senticosi was gained by continuous microwave radiation. Results: Some parameters such as microwave power, radiation time, solvent concentraction, solvent consumption, pulverized degree and dipping time had interactions on the extraction of active constituents in Radix Acanthopanacis Senticosi. Conclusion: The optimization process was obtained which could be described as following: 510W as the microwave power, 30 min as the radiation time, 85% ethanol as the solvent, 1∶5 as the proportion of raw material to solvent, 40 mesh as the grinding degree and 0.5 hr as the dipping time. Meanwhile, the model developed were proved to be reasonable by the pilot experiment.