Optimization of matrix composition and technology for Jiefushuang Emulsion / 中成药

ABSTRACT

Objective: To optimize matrix composition and technology for Jiefushuang Emulsion. Methods: Orthogonal design was used, oil phase, agitation velocity, emulsifiers and emulsify temperature were selected as variable factors. Results: The optimum matrix composition and technology were The ratio of oil to water was 2∶3, emulsifiers 320g(oil 500mL), HLB 15, emulsity temperature 70?C , agitation velocity 800 revolutions per minute, lasting for 20 minutes. Conclusion: The emulsion prepared accords with the stipulation of the appendix of Chinese pharmacopoeia (2000).