An experimental study of prophylactic and therapeutic effects of oxymatrine on dimethylnitrosamine-induced rat liver fibrosis / 中华消化杂志
Chinese Journal of Digestion
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-682013
ABSTRACT
Objective To investigate the prophylactic and therapeutic effect of oxymatrine(OM) on experimental liver fibrosis and to reveal its mechanism. Methods By establishing models of dimethylnitrosamine(DMN) induced liver fibrosis in rats, we observed the effect of oxymatrine on liver/weight index, serum and tissue biochemical indexes, content of liver hydroxyproline, expression of TGF?1 mRNA, electromicroscopic changes and tissue pathology. Results There was a decline of serum AST, ALT and liver hydroxyproline in oxymatrine group, compared to those of the DMN group( P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Digestion
Año:
2001
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS